SOCR Data April2009 ID NI

Data Overview

Neuroimaging Data

Neuroimaging MRI data from asymptomatic subjects was acquired to develop a structural brain atlas (Shattuck, et al., 2008). The raw data was processed in two different ways to test a research hypothesis that super-resolution image enhancement would improve automated volume parcellation. Thus, an automated volume parcelation (Tu, et al., 2008) was applied first to the raw data and then to the super-resolved enhanced volumes (Marquina and Osher, 2007). Two measures of quality of the automated volume parsing were used -- sensitivity and specificity.

Finally the results of the Sensitivity and Specificity measures were compared for the two analysis protocols -- applying the auto-volume parser directly to the native data (Standard method) and preprocesisng the native data with super-resolution enhancement (Super-Resolved) before using hte automated volume parser. Of interest was whether the second protocol (supre-resolved analysis) would produce more reliable, consistent and accurate automated volume tesselations, compared to the first protocol (standard method) where a super-resolution preprocessing was not applied.

Data Description

• ICV – intracranial volume
• PFC – prefrontal cortex
• GM – gray matter
• Total – total volume
• WM – white matter
• SEM – standard error of the mean

Data: Total, GM and WM volumes of ICV and PFC across species

	Cerebrum ICV (mm3)			PFC (mm3)			% PFC/ICV
	Total	GM	WM	Total	GM	WM
Human	1,206,129	535,956	670,174	156,443	82,346	74,097	12.97067%
Bonobo	272,837	125,469	147,368	25,374	15,382	9,993	9.300058%
Chimpanzee	277,843	123,858	153,985	30,324	17,234	13,091	10.91408%
Gorilla	389,681	170,505	219,176	41,655	23,419	18,235	10.68951%
Orangutan	333,075	154,293	178,781	33,763	21,193	12,570	10.13676%
Gibbon	65,938	32,418	33,520	6,302	3,994	2,307	9.557463%
Mangabey	82,495	37,985	44,510	6,599	3,804	2,794	7.999273%
Baboon	130,600	58,615	71,985	11,660	6,530	5,130	8.928025%
Macaca	69,875	31,841	38,034	5,579	2,813	2,766	7.984258%
Capuchin	58,581	29,358	29,223	5,835	3,293	2,542	9.960567%
Squirrel(monkey)	21,542	9,785	11,756	1,820	1,094	727	8.448612%

References

• Schoenemann, PT., Sheehan, MJ., Glotzer, DL. (2005) Prefrontal white matter volume is disproportionately larger in humans than in other primates. Nature Neuroscience, 8, 242–252. doi:10.1038/nn1394.

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