SOCR Data July2009 ID NI

Data Overview

Neuroimaging Data

This is a large neuroimaging study using automated volumetric data processing to obtain different shape and volume measures of local anatomy. The subject population is derived from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database and includes 27 Alzheimer's disease (AD) subjects, 35 normal controls (NC), and 42 mild cognitive impairment subjects (MCI). The goals of the study were to identify associations and relationships between neuroimaging biomarkers and various subject demographics and traits.

Data Description

• Subject_ID: index of the subject in this dataset (1, 2, 3, ..., 104)
• Group: Indicator of the subject group: Alzheimer's disease (AD), normal control (NC), or mild cognitive impairment (MCI)
• MMSE: Mini-Mental State Exam score, a cognitive assessment measure
• CDR: Clinical Dementia Rating scale
• Sex: Subject's gender label
• Age: Subject's age
• TBV: Total Brain Volume measure in mm<sum>3
• GMV: Gray Matter Volume in mm<sum>3
• WMV: White Matter Volume in mm<sum>3
• CSFV: Cerebrospinal Fluid Volume in mm<sum>3
• ROI: Label/Index of a Region of Interest (ROI)
• Measure: Labels of ROI measures:
  • SA: Surface Area of the ROI
  • SI: Shape Index of the ROI
  • CV: Curvedness of the ROI
  • FD: Fractal Dimension of the ROI
• Value: Numerical value of the measure (above).

Data

Complete data set (5MB) is available here. A small portion of the data that illustrates the complexity of this dataset is shown in the table below:

Subject_ID	Group	MMSE	CDR	Sex	Age	TBV	GMV	WMV	CSFV	ROI	Measure	Value

ROIs

Index	ImageIntensity	ROI_Name
0	0	Background
1	21	L_superior_frontal_gyrus
2	24	R_middle_frontal_gyrus
3	50	R_precuneus
4	181	cerebellum
5	47	L_angular_gyrus
6	122	R_cingulate_gyrus
7	83	L_middle_temporal_gyrus
8	90	R_lingual_gyrus
9	81	L_superior_temporal_gyrus
10	91	L_fusiform_gyrus
11	44	R_superior_parietal_gyrus
12	66	R_inferior_occipital_gyrus
13	87	L_parahippocampal_gyrus
14	162	R_caudate
15	85	L_inferior_temporal_gyrus
16	182	brainstem
17	43	L_superior_parietal_gyrus
18	28	R_precentral_gyrus
19	23	L_middle_frontal_gyrus
20	89	L_lingual_gyrus
21	41	L_postcentral_gyrus
22	86	R_inferior_temporal_gyrus
23	163	L_putamen
24	26	R_inferior_frontal_gyrus
25	102	R_insular_cortex
26	25	L_inferior_frontal_gyrus
27	46	R_supramarginal_gyrus
28	34	R_gyrus_rectus
29	65	L_inferior_occipital_gyrus
30	164	R_putamen
31	61	L_superior_occipital_gyrus
32	30	R_middle_orbitofrontal_gyrus
33	42	R_postcentral_gyrus
34	27	L_precentral_gyrus
35	32	R_lateral_orbitofrontal_gyrus
36	121	L_cingulate_gyrus
37	31	L_lateral_orbitofrontal_gyrus
38	92	R_fusiform_gyrus
39	45	L_supramarginal_gyrus
40	88	R_parahippocampal_gyrus
41	22	R_superior_frontal_gyrus
42	29	L_middle_orbitofrontal_gyrus
43	68	R_cuneus
44	62	R_superior_occipital_gyrus
45	33	L_gyrus_rectus
46	48	R_angular_gyrus
47	64	R_middle_occipital_gyrus
48	84	R_middle_temporal_gyrus
49	49	L_precuneus
50	67	L_cuneus
51	161	L_caudate
52	165	L_hippocampus
53	166	R_hippocampus
54	82	R_superior_temporal_gyrus
55	63	L_middle_occipital_gyrus
56	101	L_insular_cortex

References

• Dinov ID, Van Horn JD, Lozev KM, Magsipoc R, Petrosyan P, Liu Z, MacKenzie-Graha A, Eggert P, Parker DS and Toga AW (2009) Efficient, Distributed and Interactive Neuroimaging Data Analysis using the LONI Pipeline. Front. Neuroinform. (2009) 3:22. doi:10.3389/neuro.11.022.2009, published online: 20 July 2009.

• David W. Shattuck, Mubeena Mirza, Vitria Adisetiyo, Cornelius Hojatkashani, Georges Salamon, Katherine L. Narr, Russell A. Poldrack, Robert M. Bilder, Arthur W. Toga, Construction of a 3D probabilistic atlas of human cortical structures, NeuroImage, Volume 39, Issue 3, 1 February 2008, Pages 1064-1080, ISSN 1053-8119, DOI: 10.1016/j.neuroimage.2007.09.031.

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