SOCR Data April2009 ID NI
Contents
SOCR Datasets - Neuroimaging study of Prefrontal Cortex Volume across Species and Tissue Types
Data Overview
Neuroimaging MRI data from asymptomatic subjects was acquired to develop a structural brain atlas (Shattuck, et al., 2008). The raw data was processed in two different ways to test a research hypothesis that super-resolution image enhancement would improve automated volume parcellation. Thus, an automated volume parcelation (Tu, et al., 2008) was applied first to the raw data and then to the super-resolved enhanced volumes (Marquina and Osher, 2007). Two measures of quality of the automated volume parsing were used -- sensitivity and specificity.
Finally the results of the Sensitivity and Specificity measures were compared for the two analysis protocols -- applying the auto-volume parser directly to the native data (Standard method) and preprocesisng the native data with super-resolution enhancement (Super-Resolved) before using hte automated volume parser. Of interest was whether the second protocol (supre-resolved analysis) would produce more reliable, consistent and accurate automated volume tesselations, compared to the first protocol (standard method) where a super-resolution preprocessing was not applied.
Data Description
- ICV – intracranial volume
- PFC – prefrontal cortex
- GM – gray matter
- Total – total volume
- WM – white matter
- SEM – standard error of the mean
Data: Total, GM and WM volumes of ICV and PFC across species
| Cerebrum ICV (mm3) | PFC (mm3) | % PFC/ICV | |||||
|---|---|---|---|---|---|---|---|
| Total | GM | WM | Total | GM | WM | ||
| Human | 1,206,129 | 535,956 | 670,174 | 156,443 | 82,346 | 74,097 | 12.97067% |
| Bonobo | 272,837 | 125,469 | 147,368 | 25,374 | 15,382 | 9,993 | 9.300058% |
| Chimpanzee | 277,843 | 123,858 | 153,985 | 30,324 | 17,234 | 13,091 | 10.91408% |
| Gorilla | 389,681 | 170,505 | 219,176 | 41,655 | 23,419 | 18,235 | 10.68951% |
| Orangutan | 333,075 | 154,293 | 178,781 | 33,763 | 21,193 | 12,570 | 10.13676% |
| Gibbon | 65,938 | 32,418 | 33,520 | 6,302 | 3,994 | 2,307 | 9.557463% |
| Mangabey | 82,495 | 37,985 | 44,510 | 6,599 | 3,804 | 2,794 | 7.999273% |
| Baboon | 130,600 | 58,615 | 71,985 | 11,660 | 6,530 | 5,130 | 8.928025% |
| Macaca | 69,875 | 31,841 | 38,034 | 5,579 | 2,813 | 2,766 | 7.984258% |
| Capuchin | 58,581 | 29,358 | 29,223 | 5,835 | 3,293 | 2,542 | 9.960567% |
| Squirrel(monkey) | 21,542 | 9,785 | 11,756 | 1,820 | 1,094 | 727 | 8.448612% |
Data: Average percentage of cortical measure designated prefrontal
| Total (mm3) | GM (mm3) | WM | ||||
|---|---|---|---|---|---|---|
| mean | SEM | mean | SEM | mean | SEM | |
| Human | 12.97 | 0.3 | 14.4 | 0.3 | 10.9 | 0.4 |
| Bonobo | 9.30 | 0.3 | 11.9 | 0.4 | 6.8 | 0.4 |
| Chimpanzee | 10.91 | 0.8 | 14.1 | 1.1 | 8.3 | 0.7 |
| Gorilla | 10.68 | 0.5 | 13.7 | 0.8 | 8.3 | 0.2 |
| Orangutan | 10.13 | 0.6 | 14.1 | 0.5 | 7.5 | 0.6 |
| Gibbon | 9.55 | 0.7 | 12.3 | 1.2 | 6.9 | 0 |
| Mangabey | 7.99 | 0.6 | 9.8 | 0.7 | 6.2 | 0.8 |
| Baboon | 8.92 | 1.4 | 11.2 | 0.5 | 7.5 | 2 |
| Macaca | 7.98 | 0.6 | 8.8 | 0.3 | 7.3 | 0.9 |
| Capuchin | 9.96 | 0.1 | 11.4 | 0.5 | 8.6 | 0.2 |
| Squirrel (monkey) | 8.44 | 0.6 | 10.6 | 1 | 6.3 | 0.3 |
References
- Schoenemann, PT., Sheehan, MJ., Glotzer, DL. (2005) Prefrontal white matter volume is disproportionately larger in humans than in other primates. Nature Neuroscience, 8, 242–252. doi:10.1038/nn1394.
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