SOCR Events FTO Obesity Neuroimaging2010

SOCR News - Neuroimaging study of obesity and brain tissue loss using the SOCR computational libraries

PNAS published the largest neuroimaging study to-date identifies the relations between obesity gene (FTO) and brain tissue loss using the SOCR computational libraries.

Reporting in the journal Proceedings of the National Academy of Sciences, UCLA investigators found that the FTO obesity gene is associated with a loss of brain tissue. This puts more than a third of the U.S. population at risk for a variety of diseases, such as Alzheimer's. This study used the SOCR computational libraries and SOCR Analyses to

See also

• PNAS Paper (April 2010): April J. Ho, Jason L. Stein, Xue Hua, Suh Lee, Derrek P. Hibar, Alex D. Leow, Ivo D. Dinov, Arthur W. Toga, Andrew J. Saykin, Li Shen, Tatiana Foroud, Nathan Pankratz, Matthew J. Huentelman, David W. Craig, Jill D. Gerber, April N. Allen, Jason J. Corneveaux, Dietrich A. Stephan, Charles S. DeCarli, Bryan M. DeChairo, Steven G. Potkin, Clifford R. Jack, Jr., Michael W. Weiner, Cyrus A. Raji, Oscar L. Lopez, James T. Becker, Owen T. Carmichael, Paul M. Thompson, and the Alzheimer's Disease Neuroimaging Initiative. (2010) A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. PNAS published ahead of print April 19, 2010, doi:10.1073/pnas.0910878107.
• Genetic Engineering and Biotechnology News
• ABC7, Eyewitness News
• NPR (April 2010)

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• SOCR Home page: http://www.socr.ucla.edu

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